Proteofection – as the direct transport of proteins into living eukaryotic cells is known – is a versatile alternative to transfection of nucleic acids and opens up a range of completely new options in research into eukaryotic cell processes.
Biontex has developed cationic lipids aligned to proteins, and specifically their surface structures, and used them to produce new lipid-based formulas which spontaneously bind with proteins to form protein-lipid complexes known as proteoplexes. In an analogous process to transfection, these proteoplexes are actively taken up by eukaryotic cells by means of endocytosis and transported into the cell interior. Both the proteins and the antibodies, with structure and function completely unchanged, are released from the endosomes to develop their activity there.
Biontex supplies PROTEOfectene™ (cat. no. E010) for proteins and PROTEOfectene™ AB (cat. no. E020) for antibodies, two revolutionary lipid-based reagents in the research field of proteomics and for research into functional relationships of proteins.
Biontex offers brand new products in the field of gene transfection, protein transfection and transfection for microscopy studies. See our new products
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